Brain scans using Amyvid dye to highlight beta-amyloid plaques in the brain. Clockwise from top left: a cognitively normal subject; an amyloid-positive patient with Alzheimer's disease; a patient with mild cognitive impairment who progressed to dementia during a study; and a patient with mild cognitive impairment.
It's been a mixed year for Alzheimer's research. Some promising drugs failed to stop or even slow the disease. But researchers also found reasons to think that treatments can work if they just start sooner.
Scientists who study Alzheimer's say they aren't discouraged by the drug failures. "I actually think it was a phenomenal year for research," says Bill Rebeck, a brain scientist at Georgetown University.
Brazilian health officials say an epidemic is taking hold — an outbreak of crack cocaine use nationwide, from the major cities on the coast to places deep in the Amazon.
It's an image at odds with the one Brazil wants to project as the country prepares to host soccer's World Cup in 2014 and the Summer Olympics two years later. But the problem has become too big to ignore.
The Luz district of central Sao Paulo was once grand, with its old train station and opulent buildings. Now, this neighborhood is known as Cracolandia — Crackland.
Originally published on Mon December 31, 2012 2:42 pm
Managing food allergies can be a pain, requiring lots of sleuthing of ingredients in restaurants and supermarkets. But people with potentially lethal allergies to nuts and other foods don't have much choice.
Dozens of smartphone apps offer to make that task easier. Doctors say, though, the apps now on the market just aren't reliable enough.
Starting next summer, aspiring commercial pilots will need 1,500 hours of flight training before they can be hired. This dramatic increase, among other factors, is making airlines worry that there will not be enough pilots to maintain current service.
Some airlines — especially the smaller ones — worry they won't have enough pilots. They're a number of factors in play, but they point to new federal safety rules as a big part of the problem.
In February 2009, a Colgan Air commuter jet crashed, killing 50 people. Investigators cited inadequate pilot training; Congress responded with new legislation. Beginning next summer, those who want to pilot commercial jets will need dramatically more hours of flight training before they can be hired.
Originally published on Tue January 1, 2013 11:03 am
As the nation's first African-American president, Barack Obama benefited from and expanded his party's enormous advantage among minority voters.
But as he prepares to start his second term, Obama hasn't managed to usher in behind him many Democrats who are minorities to top elected office. Conversely, Republicans — despite their highly limited support among non-Anglo voters — have managed to elevate more top politicians from minority backgrounds.
Originally published on Wed December 26, 2012 1:49 pm
President Obama is "cutting short" a vacation that he'd already said he would cut short. "See you next week," he told reporters last week before leaving for Hawaii. The president is now due back at the White House on Thursday, which is pretty much what was expected. His family will stay in Hawaii until after the New Year.
Senators are also coming back to Washington, but many aren't likely to get to the Capitol until Thursday evening.
This is TALK OF THE NATION. I'm Ari Shapiro in Washington. Neal Conan is away. This week, many of us are making year-end charitable donations. There are countless needy people and worthy causes competing for our dollars. So many philanthropists today want proof that an organization actually succeeds at its mission.
Originally published on Wed December 26, 2012 1:46 pm
NPR's Political Junkie Ken Rudin recaps the week in politics and reflects on some of the significant political moments of the year. He also faces off in a trivia battle with burgeoning political junkie Gabe Fleisher, a fifth grader who drafts a political newsletter everyday before school.
Originally published on Wed December 26, 2012 1:54 pm
Alcestis 'Cooky' Oberg lost her father-in-law unexpectedly on Christmas Day in 1982. For the first few years, it meant that Christmas was a somber time. Oberg, a contributor to USA Today, talks about how the mood of the holidays evolved for her family over time.